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Acyclovir eye ointment is indicated for the treatment of Herpes Simplex Keratitis.
Ophthalmic Anti-viral Products
Acyclovir is a synthetic purine nucleotide analogue, which acts against human herpes viruses. The enzyme thymidine kinase (TK)encoded by HSV, VZV and EBV convert acyclovir into acyclovir monophosphate, a nucleotide analogue, which is further converted to diphosphate and triphosphate by cellular enzymes. Acyclovir triphosphate interferes with DNA polymerase and inhibits viral DNA replication with resultant chain termination following its incorporation into the growing viral DNA chain.
Dosage & Administration
Apply ointment into lower conjunctival sac five times daily at 4 hours interval; continue for minimum 3 days after healing.
Probenecid, cimetidine and mycophenolate mofetil may increase the plasma concentration of aciclovir. Increased nephrotoxic effects with drugs that affect renal physiology (e.g. ciclosporin, tacrolimus)
It is contraindicated to the patients with known hypersensitivity to acyclovir.
- Store Name: Dooari Pharma
- Vendor: Dooari Pharma
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